发明名称 ALTERNATE CRYSTAL FORM OF TAZOFELONE
摘要 The instant invention provides novel crystalline Form II of (+/-)-5-{¢3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl!methyl}-4-thiazolidinone having an xray powder diffraction pattern with d spacings at 5.64.ANG., 5.16.ANG., 4.90.ANG., 4.66.ANG. and 4.49.ANG. is useful for treating inflammation, inflammatory bowel disease, allergies, arthritis and hypoglycemia utilizing the novel physical form as well as pharmaceutical compositions containing the same. A process for preparing Form II Tazofelone is described.
申请公布号 CA2231132(A1) 申请公布日期 1997.03.13
申请号 CA19962231132 申请日期 1996.09.03
申请人 ELI LILLY AND COMPANY 发明人 REUTZEL, SUSAN MARIE;HARKNESS, ALLEN ROBERT;HANSEN, MARVIN MARTIN
分类号 A61K31/00;A61K31/425;A61K31/426;A61P29/00;C07D277/14;(IPC1-7):C07D277/14 主分类号 A61K31/00
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