发明名称 |
Alternate crystal form of tazofelone ((+,-)-5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methyl)-4-thiazolidinone) |
摘要 |
<p>The instant invention provides novel crystalline Form II of (+/-)-5-äÄ3,5-bis(1,1-dimethylethyl)-4-hydroxyphenylÜmethylü-4-thiazol idinone having an x-ray powder diffraction pattern with d spacings at 5.64 ANGSTROM , 5.16 ANGSTROM , 4.90 ANGSTROM , 4.66 ANGSTROM and 4.49 ANGSTROM is useful for treating inflammation, inflammatory bowel disease, allergies, arthritis and hypoglycemia utilizing the novel physical form as well as pharmaceutical compositions containing the same. A process for preparing Form II Tazofelone is described.</p> |
申请公布号 |
EP0761656(A1) |
申请公布日期 |
1997.03.12 |
申请号 |
EP19960306336 |
申请日期 |
1996.09.02 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
HANSEN, MARVIN MARTIN;HARKNESS, ALLEN ROBERT;REUTZEL, SUSAN MARIE |
分类号 |
A61P29/00;A61K31/00;A61K31/425;A61K31/426;C07D277/14;(IPC1-7):C07D277/14 |
主分类号 |
A61P29/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|