| 发明名称 |
CELL-CYCLE CHECKPOINT GENES |
| 摘要 |
This invention relates to a class of checkpoint genes and their polypeptide products which control progression through the cell cycle in eukaryotic cells. In particular this invention relates to Schizosaccharomyces pombe rad3 gene, to its human homologue (ATR) and to their encoded proteins. The invention further relates to assay methods for selecting compounds which modulate the activity of the polypeptide products of these checkpoint genes and the use of the selected compounds in anticancer therapy.
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| 申请公布号 |
CA2231190(A1) |
申请公布日期 |
1997.03.13 |
| 申请号 |
CA19962231190 |
申请日期 |
1996.09.06 |
| 申请人 |
ICOS CORPORATION;ICOS CORP |
发明人 |
CARR, ANTONY MICHAEL |
| 分类号 |
G01N33/53;A61K38/00;A61K39/395;A61K48/00;C07K14/39;C07K16/40;C12N1/19;C12N9/12;C12N15/09;C12N15/54;C12Q1/48;C12Q1/68;G01N33/15;(IPC1-7):C12N15/54;G01N33/573;G01N33/574 |
主分类号 |
G01N33/53 |
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