发明名称 |
AZOLE DERIVATIVES, THEIR USE, PRODUCTION AND USAGE |
摘要 |
The present invention relates to an azole derivative represented by the general formula (I): <IMG> (I) ¢wherein each of R1, R2 and R3 is H, halogen, C1-8alkyl or the like, and A is a group represented by the formula (i) or (ii): <IMG> <IMG> (i) (ii) (wherein R4, R5, R6 and X are as defined in the specification.)! and a pharmacologically acceptable salt thereof, which have ACAT-inhibitory activity and are useful as a prophylactic and therapeutic agent for hypercholesterolemia, atherosclerosis and various diseases caused by them; a process for producing said derivative; and an ACAT inhibitor containing said derivative or salt as an active ingredient.
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申请公布号 |
CA2185082(A1) |
申请公布日期 |
1997.03.12 |
申请号 |
CA19962185082 |
申请日期 |
1996.09.09 |
申请人 |
NIHON NOHYAKU CO., LTD. |
发明人 |
YAMAMOTO, KENJI;KONDOH, KUNIAKI;HORIUCHI, KENJI;MATSUI, YOSHIMITSU;NAGAMINE, MASASHI |
分类号 |
C07D277/48;C07D233/88;C07D263/48;C07D277/46;C07F7/08;(IPC1-7):C07D277/48;A61K31/695;A61K31/535;C07F7/10;A61K31/445;A61K31/41 |
主分类号 |
C07D277/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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