发明名称 AZOLE DERIVATIVES, THEIR USE, PRODUCTION AND USAGE
摘要 The present invention relates to an azole derivative represented by the general formula (I): <IMG> (I) ¢wherein each of R1, R2 and R3 is H, halogen, C1-8alkyl or the like, and A is a group represented by the formula (i) or (ii): <IMG> <IMG> (i) (ii) (wherein R4, R5, R6 and X are as defined in the specification.)! and a pharmacologically acceptable salt thereof, which have ACAT-inhibitory activity and are useful as a prophylactic and therapeutic agent for hypercholesterolemia, atherosclerosis and various diseases caused by them; a process for producing said derivative; and an ACAT inhibitor containing said derivative or salt as an active ingredient.
申请公布号 CA2185082(A1) 申请公布日期 1997.03.12
申请号 CA19962185082 申请日期 1996.09.09
申请人 NIHON NOHYAKU CO., LTD. 发明人 YAMAMOTO, KENJI;KONDOH, KUNIAKI;HORIUCHI, KENJI;MATSUI, YOSHIMITSU;NAGAMINE, MASASHI
分类号 C07D277/48;C07D233/88;C07D263/48;C07D277/46;C07F7/08;(IPC1-7):C07D277/48;A61K31/695;A61K31/535;C07F7/10;A61K31/445;A61K31/41 主分类号 C07D277/48
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