发明名称 |
Antagonists of the oncogenic activity of the mdm2 protein and their use in the treatment of cancers |
摘要 |
The present invention relates to the utilization of a compound capable of antagonizing at least partially the oncogenic activity of the protein Mdm2 for the preparation of a pharmaceutical composition intended more particularly to a treatment of cancers with no p53 context. It further relates to the viral vector comprising a nucleic acid sequence coding for a compound capable of inhibiting at least partially the oncogenic activity of the protein Mdm2, and to a corresponding pharmaceutical composition. |
申请公布号 |
ZA9607451(B) |
申请公布日期 |
1997.03.10 |
申请号 |
ZA19960007451 |
申请日期 |
1996.09.03 |
申请人 |
RHONE-POULENC RORER SA;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE |
发明人 |
BRUNO TOCQUE;MARIE-CHRISTINE DUBS-POTERSZMAN;BOHDAN WASYLYK |
分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K45/00;A61P35/00;C07K14/47;C07K14/82;C07K16/00;C07K16/32 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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