摘要 |
<p>Methods and compositions for the treatment and diagnosis of viral infections are provided. These methods and compositions utilize the ability of Rev binding nucleic acids such as the SL II sequence from the HIV-1 Rev Response Element (RRE) to target therapeutic agents to the same sub-cellular location as viruses which contain RRE sequences. The use of the compositions of the invention as components of diagnostic assays, as prophylactic reagents, and in gene therapy vectors is also described.</p> |