发明名称 |
EFFICIENT ENRICHMENT AND DETECTION OF DISSEMINATED TUMOR CELLS |
摘要 |
Tumor cells, particularly carcinoma cells, are separated from peripheral blood by magnetic sorting. The tumor cells are magnetically labeled with antibodies directed to tissue specific antigens, preferably cytoplasmic proteins. Labeling for cytoplasmic antigens is accomplished first permeabilizing, then fixing the cells. The cells are separated on a magnetic matrix. The number of tumor cells in the enriched fraction is used to calculate the number of tumor cells present in a patient hematopoietic sample.
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申请公布号 |
CA2229001(A1) |
申请公布日期 |
1997.03.06 |
申请号 |
CA19962229001 |
申请日期 |
1996.08.23 |
申请人 |
AMCELL CORPORATION;MILTENYI BIOTECH GMBH |
发明人 |
KANTOR, AARON;QIAN, FAWN;MILTENYI, STEFAN;SCHMITZ, JURGEN |
分类号 |
G01N33/543;G01N33/574;(IPC1-7):C12N5/08;C12N5/06;G01N33/554 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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