SUBSTITUTED CYCLIC UREAS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS

摘要

The present invention relates to substituted cyclic ureas and analogs thereof of formula (I), wherein T is selected from: -N(R22)C(=Z)N(R23)-; -N(R22)C(=Z)C(=Z)N(R23)-; -N(R22)S(=Z')N(R23)-; -N(R22)S(=Z')¿2N(R?23)-; or -N(R22)P(=O)(R?24a)N(R23¿)-; Z is O, S, NR24; and Z' is O or NR24; or pharmaceutically acceptable salt forms or prodrugs thereof, which are useful as retroviral protease inhibitors, and to pharmaceutical compositions comprising such compounds and methods of using the same for treating viral infection.