CHIMERIC ANIMAL AND METHOD FOR CONSTRUCTING THE SAME

摘要

A method for constructing a chimeric nonhuman animal which comprises preparing microcells containing one or more foreign chromosomes or fragments of the same, and transferring the foreign chromosome(s) or fragments of the same into cells having differentiative pluripotency via the fusion with the microcells; a chimeric nonhuman animal which can be constructed by the above method and offsprings of the same; tissues and cells originating in the same; a method for utilizing the tissues and cells; cells which contain one or more foreign chromosomes or fragments of the same and sustain differentiative pluripotency; a method for constructing the cells; and a method for utilizing the cells.