| 摘要 |
An implantable drug delivery apparatus including a housing that has a housing chamber. An outer deformable body having a reserve chamber is mounted within the housing chamber. An inner deformable body having a dispensing chamber is mounted within the reserve chamber. A dispensing valve is actuated to an open position to allow a fluidic drug to flow from the dispensing chamber, through the dispensing valve and through a catheter into a body of a patient. The fluidic drug is discharged from the dispensing chamber at a dispensing mass flowrate which is greater than a refilling mass flowrate of the fluidic drug passing from the reserve chamber to the dispensing chamber, when the dispensing valve is in an open position. When the dispensing valve is in a closed position, the fluidic drug is prevented from discharging from the dispensing chamber while a recharging amount of the fluidic drug is capable of flowing from the reserve chamber to the dispensing chamber, until the dispensing chamber is at least partially filled. The outer deformable body is normally forced or urged in a direction or manner that tends to reduce a volume of the reserve chamber.
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