SOLID COMPLEX PARTICLES COMPRISING A BIOLOGICALLY ACTIVE SOLID SUBSTANCE, MODE OF PREPARATION AND COMPOSITIONS FOR TOPICAL USE CONTAINING THEM AND INTENDED TO TREAT BIOLOGICAL SURFACES

摘要

The present invention relates to solid complex particles each comprised of at least two solid substances, at least one of them being biologically active. The biologically active solid substance is comprised of at least one biologically active product and is evenly distributed at the surface of a grain consisting of the other solid core-forming substance, so-called support substance, said grain having a size comprised between 0.05 and 100 mu m (microns) and the weight ratio between said active substance and said core-forming substance being comprised between 10<-4> and 1.5 approximately. The invention also relates to a method for the preparation of said particles, a process for the treatment of a biological surface in order to accelerate the biodisponibility of a biologically active substance. It also relates to compositions for topical application containing the particles of the invention.