PEPTIDES INHIBITING PHOSPHOLIPASE C

摘要

Peptides inhibiting phospholiphase C which are represented by general formula (I), wherein n represents 0 or 1; J<1> and J<2> represent each hydrogen or form together a single bond; W represents hydrogen, optionally substituted alkanoyl, optionally substituted aroyl or coumaryl; X represents a single bond, -Leu- or -Ser-Leu-Val-Glu-Leu-Val-Ser-Tyr-Tyr-Glu-Lys-His-Ala-Leu optionally having the deletion, insertion or replacement of at least one amino acid residue; Y represents a single bond or -Pro-Val-; R<1> represents hydrogen, optionally substituted alkyl or optionally substituted aryl; and R<2> represents optionally substituted alkyl or optionally substituted aryl. <CHEM>