| 发明名称 |
REVERSAL OF MULTI-DRUG RESISTANCE BY TETRAARYLETHYLENES. |
| 摘要 |
<p>Certain tetraarylethylenes reverse drug resistance in multi-drug resistant tumors. These compounds apparently function by inhibiting a p-glycoprotein pump which becomes activated in late stage tumor development and which is inherently present in tumors from certain origins.</p> |
| 申请公布号 |
GR3021811(T3) |
申请公布日期 |
1997.02.28 |
| 申请号 |
GR19960403202T |
申请日期 |
1996.11.28 |
| 申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
SUNKARA, SAI, P. |
| 分类号 |
C07D295/08;A61K31/135;A61K31/138;A61K31/40;A61K31/44;A61K31/4402;A61K31/4418;A61K31/445;A61K31/495;A61K31/535;A61K31/5375;A61P35/00;C07D213/24;(IPC1-7):A61K31/44 |
主分类号 |
C07D295/08 |
| 代理机构 |
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代理人 |
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| 地址 |
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