发明名称 POLYCARBONATES AND THE USE THEREOF FOR THE PREPARATION OF BIOEROSIBLE MATRICES
摘要 <p>PCT No. PCT/EP92/01262 Sec. 371 Date Dec. 10, 1993 Sec. 102(e) Date Dec. 10, 1993 PCT Filed Jun. 5, 1992 PCT Pub. No. WO92/22600 PCT Pub. Date Dec. 23, 1992.Polycarbonates of formula (I) wherein a is an integer from 2 to 300; R1 and R2 are the same or different and are independently a polyester residue of formula (III) wherein x and y are integers from 1 to 50, R4 and R5, which are the same or different, are aliphatic straight or branched hydrocarbon chains having from 1 to 4 carbon atoms, R6 is an aliphatic or alicyclic straight or branched chain having from 2 to 18 carbon atoms, or a polyoxyalkylene residue of formula (II), the two groups -R4-COO and -R5-COO being randomly distributed in the polyester residue, x and y being in any possible ratio from 0 to 100, are synthesized by reacting dihydroxy compounds with 1,1'-carbonyldiimidazole. They are useful for the preparation of bioerosible matrices for biologically active compounds. <IMAGE> (I) <IMAGE> (II) <IMAGE> (III)</p>
申请公布号 GR3021602(T3) 申请公布日期 1997.02.28
申请号 GR19960402980T 申请日期 1996.11.13
申请人 MEDIOLANUM FARMACEUTICI S.P.A. 发明人 FERRUTI, PAOLO;RANUCCI, ELISABETTA;BIGNOTTI, FABIO
分类号 A61K9/20;A61K9/22;A61K47/34;C08G63/64;C08G64/00;C08G64/02;C08G64/18;C08G64/38;(IPC1-7):C08G64/02 主分类号 A61K9/20
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