| 摘要 |
<p>1S,4S and 1R,4R-2-Alkyl-2,5-diazabicyclo[2.2.1]-heptanes of the relative or absolute stereochemical formula (I) useful as intermediates in the synthesis of certain antibacterial quinolones, are prepared respectively, from trans-4-hydroxy-L-proline and trans-4-hydroxy-D-proline of the relative or absolute stereochemical formula (II) via multistep procedures. <CHEM> wherein R is (C1-C6)alkyl: R<2> is (C1-C6)alkyl,trifluoromethyl or <CHEM> S</p> |
