发明名称 |
DERIVATISIERTE GLASTRÄGER ZUR SEQUENZIERUNG VON PEPTIDEN UND PROTEINEN |
摘要 |
Peptides or proteins are sequenced by stepwise degradation while immobilized on a glass support derivatized with a silica-binding substance bearing a free acid group, especially a sulfonic acid group. The support is preferably derivatized with 2-(4-chlorosulfonyl phenyl) ethyl trimethoxysilane. Peptide sequencing performance is improved if the support is also derivatized with a monomeric silica-binding substance bearing a free quaternary ammonium group, such as N-trimethyoxysilyl propyl -N,N,N-trimethyl ammonium chloride. |
申请公布号 |
DE68927403(T2) |
申请公布日期 |
1997.02.27 |
申请号 |
DE1989627403T |
申请日期 |
1989.08.04 |
申请人 |
BECKMANN INSTRUMENTS INC., FULLERTON, CALIF., US |
发明人 |
FARNSWORTH, VINCENT, AGOURA, CA 91301, US |
分类号 |
G01N33/68;C07K1/12;G01N33/552;(IPC1-7):G01N33/68;B32B17/06 |
主分类号 |
G01N33/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|