| 摘要 |
<p>The present invention is a method of diagnosing the presence of a persistent occlusion in a myocardial infarct patient undergoing thrombolytic therapy. The method comprises detecting a series of five variables from the patient and then generating the probability of the presence of a persistent occlusion from those variables. The first variable comprises a serum creatine kinase MB (CK-MB) level (10) from a patient at the onset of thrombolytic therapy. The second variable comprises a second CK-MB level (20) in the patient at a predetermined time after the onset of thrombolytic therapy. The third variable comprises the presence or absence of chest pain (50) a predetermined time after the onset of thrombolytic therapy. The fourth variable comprises the serum myoglobin level (30) in the patient at a predetermined time after the onset of thrombolytic therapy. In a preferred embodiment of the present invention, the second, third and fourth variables are detected within 30 minutes of each other and within about 1 hour to 3 hours after the initial variable is detected. In an alternate embodiment a fifth variable reflecting the time from onset of chest pain to the beginning of thrombolytic therapy is included in the regression model.</p> |
