| 摘要 |
<p>A method of conducting fixed-bed enzymatic reactions by bringing a substrate into contact with an enzyme immobilized on a carrier packed in a reactor while keeping the optimum temperature of the enzyme, which method comprises conducting the reaction under adiabatic conditions, and simultaneously mixing part of the reaction fluid with a substrate solution and circulating the resultant mixture to the reactor through a heat exchanger, thereby holding the inside of the reactor in a state as homogeneous as possible. The method makes it possible to narrow the temperature range in the reactor and to conduct enzymatic reactions at a temperature near the optimum temperature of the employed enzyme under the condition of a high enzymatic activity.</p> |
