| 摘要 |
The invention discloses compounds useful as non-steroidal sulfatase inhibitors. The compounds comprise formula (1), wherein (a) R1 is selected from the group consisting of hydrogen and a lower alkyl group, (b) R2 is selected from the group consisting of H and a lower alkyl group, (c) m is an integer from 0 to 4, and (d) n is an integer from 5 to 14. R1 is selected from the group consisting of H and C1-C6 alkyl and R2 is selected from the group consisting of H and C1-C6 alkyl. The invention also discloses methods of treating a patient prophylactically to provide protection as en estrogen depleting agent for estrogen dependent illnesses and treating a patient therapeutically for estrogen dependent diseases. A method of making the non-steroidal sulfatase inhibitors is also disclosed.
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