发明名称 |
Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester, and intermediate therefor |
摘要 |
Optically active acyloxysuccinic anhydride is reacted with an aromatic compound in the presence of a Lewis acid to produce an optically active 2-acyloxy-4-oxo-4-arylbutyric acid, which can then be converted into an optically active 2-acyloxy-4-arylbutyric acid by catalytic reduction, and the latter compound hydrolyzed in the presence of an acid or an alkali to produce an optically active 2-hydroxy-4-arylbutyric acid, which can optionally be reacted with an alcohol in the presence of an acid to produce an optically active 2-hydroxy-4-arylbutyric acid ester. |
申请公布号 |
EP0759424(A1) |
申请公布日期 |
1997.02.26 |
申请号 |
EP19960306057 |
申请日期 |
1996.08.20 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
KURAUCHI, MASAHIKO;HAGIWARA, YOSHIMASA;MATSUEDA, HIROYUKI;NAKANO, TAKASHI;IZAWA, KUNISUKE |
分类号 |
B01J27/125;C07B53/00;C07B61/00;C07C51/083;C07C51/377;C07C59/205;C07C67/08;C07C67/293;C07C67/317;C07C67/343;C07C69/157;C07C69/732 |
主分类号 |
B01J27/125 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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