| 摘要 |
Disclosed is a technically simple method of preparing, in very good yields, highly pure N-phosphonomethylglycine esters, having a herbidical action, of formula (I) (HO)2P(O)-CH2-NH-CH2-CO-O-R, in which R is alkyl, by reacting N-phosphonomethylglycine formula (II) (HO)2P(O)-CH2-NH-CH2-COOH with alcohols of general formula (III) HO-R at temperatures between 40 and 150 DEG C in the presence of an acid (1st stage) and then reacting, at temperatures between 0 and 60 DEG C, the acid adducts of the compounds of formula (I), optionally after isolating them, with an oxiran (epoxide) used as an acid binder (2nd stage). |
