Method of preparing 2'-O-methyl cytidine monomers useful in oligomer synthesis

摘要

Methods of preparing N4-alkanoyl, aroyl and aralkanoyl 2'-O-methylcytidine derivatives are provided. Also provided are novel cytidine derivatives and nucleoside monomers comprising these cytidine derivatives which are useful in the synthesis of Oligomers, including oligonucleotides and methylphosphonate Oligomers.