发明名称 |
Somatic mutations in neurofibromatosis type 1 gene in human tumors |
摘要 |
The present invention is directed to somatic mutations of the NF1 gene which are found in human tumors. In addition, the present invention is directed to methods of screening humans to determine those having somatic mutations in the NF1 gene in tumors. Finally, the invention is directed to a method of treating a human having a tumor with a somatic mutation in the NF1 gene by restoring natural regulation of ras proteins.
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申请公布号 |
US5605799(A) |
申请公布日期 |
1997.02.25 |
申请号 |
US19950411389 |
申请日期 |
1995.03.28 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
WHITE, RAYMOND L.;CAWTHON, RICHARD M.;LI, YING |
分类号 |
C07K14/47;C12Q1/68;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04;C12N15/00 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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