发明名称 USE OF ALICYCLIC DIAMINES AS IMMUNOMODULATORS
摘要 The invention discloses the use of a compound of general structural formula (I) R-NH-K-Q-K-NH-R, wherein Q is a divalent radical of formulae (II) to (V), K is a methylene group, or, when Q is a group of formula (II), K is a binding valency. R is a radical selected from the group comprising benzyl, benzyl substituted with halogen or trihalomethyl groups, substituted trihalomethyl benzyl, indanyl, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, cycloalkenylalkyl, bicycloalkyl, bicycloalkenylalkyl, bicycloalkylalkyl; and the organic or mineral acid addition salts thereof. The preparation of a medicament for correcting the expression of cytokine genes and/or a receptor thereof for treating a dysfunction related to an exogenous or endogenous disease state is also described.
申请公布号 WO9705859(A2) 申请公布日期 1997.02.20
申请号 WO1996FR01242 申请日期 1996.08.02
申请人 NEOVACS;MAZIERE, JEAN-CLAUDE;ACHOUR, AMAR;LANDUREAU, JEAN-CHARLES;ZAGURY, DANIEL 发明人 MAZIERE, JEAN-CLAUDE;ACHOUR, AMAR;LANDUREAU, JEAN-CHARLES;ZAGURY, DANIEL
分类号 A61K45/00;A61K31/00;A61K31/13;A61K31/132;A61K31/137;A61K31/505;A61K31/513;A61P33/00;A61P33/02;A61P33/06;A61P33/12;A61P35/00;A61P35/02;A61P37/00;A61P37/04;A61P43/00 主分类号 A61K45/00
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