发明名称 SELECTIVE PROCESS FOR THE DEACYLATION OF ACYLATED COMPOUNDS
摘要 The invention provides a simple and selective method for the deacylation of 4-acylated statins during the preparation of statins from a fermentation broth, more specifically a reduction of impurities from the process, by increasing the pH of the fermentation broth.
申请公布号 WO9706128(A1) 申请公布日期 1997.02.20
申请号 WO1996EP03495 申请日期 1996.08.05
申请人 GIST-BROCADES B.V.;DE PATER, ROBERTUS, MATTHEUS;SIBEYN, MIEKE 发明人 DE PATER, ROBERTUS, MATTHEUS;SIBEYN, MIEKE
分类号 A61K35/74;C07C67/317;C07C69/732;C12P7/62;C12R1/66;(IPC1-7):C07C69/732 主分类号 A61K35/74
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