发明名称 |
SELECTIVE PROCESS FOR THE DEACYLATION OF ACYLATED COMPOUNDS |
摘要 |
The invention provides a simple and selective method for the deacylation of 4-acylated statins during the preparation of statins from a fermentation broth, more specifically a reduction of impurities from the process, by increasing the pH of the fermentation broth.
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申请公布号 |
WO9706128(A1) |
申请公布日期 |
1997.02.20 |
申请号 |
WO1996EP03495 |
申请日期 |
1996.08.05 |
申请人 |
GIST-BROCADES B.V.;DE PATER, ROBERTUS, MATTHEUS;SIBEYN, MIEKE |
发明人 |
DE PATER, ROBERTUS, MATTHEUS;SIBEYN, MIEKE |
分类号 |
A61K35/74;C07C67/317;C07C69/732;C12P7/62;C12R1/66;(IPC1-7):C07C69/732 |
主分类号 |
A61K35/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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