发明名称 |
DERIVATIVES OF AMIDINE, MIXTURE OF THEIR ISOMERS OR INDIVIDUAL ISOMERS AND THEIR SALTS, PHARMACEUTICAL COMPOSITION EXHIBITING ANTAGONISTIC ACTIVITY WITH RESPECT TO LEUKOTRIENE BACTIVITY |
摘要 |
FIELD: organic chemistry. SUBSTANCE: product: derivatives of amidine of the general formula (I) Bwhere:, B were given in the claim description, mixture of their isomers or individual isomers and their salts. Other object of invention is pharmaceutical composition exhibiting antagonistic activity with respect to leukotriene R-Ractivity that contains active substance and at least one pharmaceutically tolerated solid or liquid carrier. An active substance - compound of the general formula (I) Bindicated above, mixture of its isomers or individual isomers or its physiologically tolerated salt taken at effective amount. EFFECT: improved method of synthesis, enhanced effectiveness. |
申请公布号 |
RU94041836(A) |
申请公布日期 |
1997.02.20 |
申请号 |
RU19940041836 |
申请日期 |
1993.01.14 |
申请人 |
BERINGER INGEL'KHEJM KG |
发明人 |
RAL'F ANDERSKEVITTS;KURT SHROMM[;EHRNET-OTTO RENT;FRANK KHIMMEL'SBAKH;FRANTS BIRKE;ARMIN FJUGNER |
分类号 |
C07C257/18;A61K31/155;A61K31/34;A61K31/343;A61K31/35;A61K31/352;A61K31/357;A61K31/40;A61K31/415;A61K31/42;A61K31/421;A61K31/44;A61P1/04;A61P11/00;A61P11/06;A61P17/06;A61P29/00;A61P37/08;C07C303/40;C07C311/29;C07C315/04;C07C317/18;C07C317/22;C07C317/44;C07C319/20;C07C323/18;C07C323/20;C07C323/32;C07C323/62;C07D213/78;C07D231/00;C07D263/32;C07D277/00;C07D307/78;C07D307/79;C07D311/22;C07D317/66;C07D319/18;C07D333/38 |
主分类号 |
C07C257/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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