Process for the inactivation of carboxypeptidase Y in hirudin-containing culture broth
摘要
Inactivation of carboxypeptidase Y (CPY) in a hirudin-contg. culture broth produced by culturing a transformed yeast is effected by passing the culture broth through a tube which has a heating section, a "residence time" section and a cooling section and in which the broth is heated to 80-100 degrees C.
申请公布号
EP0758655(A1)
申请公布日期
1997.02.19
申请号
EP19960112611
申请日期
1996.08.05
申请人
HOECHST AKTIENGESELLSCHAFT
发明人
CRAUSE, PETER, DR.;HABERMANN, PAUL, DR.;MOELLER, JOERG, DR.;ULMER, WOLFGANG, DR.