| 摘要 |
A method is provided for rapidly measuring change in T2* in a region of an MR imaging subject, the method employing a double gradient echo sequence with spiral readout. In this technique, two gradient echoes are acquired after a single RF excitation. A first readout trajectory spirals out from the center of k-space, i.e., kr=0, to some maximum radius, and then a second readout trajectory spirals back towards the center of k-space. A gradient echo is formed each time a k-space trajectory passes through the center of k-space. The signal intensity of the two echoes allows the calculation of the T2* values on a pixel by pixel basis. The ability to measure changes in T2* allows measurement of change in perfusion to be quantified.
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