Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide

摘要

The present invention relates to the epimers: (22R)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5 alpha -androst-1-ene-17 beta -carboxamide and (22S)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5 alpha -androst-1-ene-17 beta -carboxamide useful as inhibitors of testosterone 5 alpha -reductase enzyme, to a process for their preparation and to pharmaceutical compositions containing them.