发明名称 Cardiotropic radiopharmaceuticals comprising a transition metal nitride complex and having rapid myocardial clearance
摘要 PCT No. PCT/FR96/01103 Sec. 371 Date Jan. 16, 1998 Sec. 102(e) Date Jan. 16, 1998 PCT Filed Jul. 16, 1996 PCT Pub. No. WO97/03705 PCT Pub. Date Feb. 6, 1997The present invention relates to cardiac tropism radiopharmaceutical products incorporating a nitride complex os a transition metal and having a rapid myocardial clearance. These complexes are based on the formula:(M 3BOND N)L1L2 (I)in which M is a transition metal such as 99mTc and L1 and L2 comply with the formula: in which at least one of the R and R' represents a branched alkyl group having one or more ether functions, a tetrahydrofurfuryl or ether group, a tetrahydrofurfuryl or dioxaspiro or dialkoxy piperidino groups.
申请公布号 AU6617896(A) 申请公布日期 1997.02.18
申请号 AU19960066178 申请日期 1996.07.16
申请人 CIS BIO INTERNATIONAL 发明人 EMMANUEL BELLANDE;JACQUES LAINE;VERONIQUE COMAZZI;ROBERTO PASQUALINI
分类号 A61K51/00;A61K51/04 主分类号 A61K51/00
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