Method for producing optically active endo-2-norborneols

摘要

The present invention provides a method for producing optically active endo-2-norborneols, represented by the following formula: <IMAGE> and the antipodes, it comprises asymmetrically hydrolysing racemic endo-2-acyloxynorbornane or endo-2-acyloxynorbornane, whose (R)-compound is in excess, having an optical purity of 50-95% ee with lipase derived from Candida genus. The optically active endo-2-norborneol useful for synthesizing intermediates of pharmaceutical preparations in large quantities.