发明名称 |
Thermophilic fungal expression system |
摘要 |
The present invention relates to recombinant thermophilic host cells comprising a nucleic acid sequence encoding a heterologous protein, and a method of producing recombinant protein utilizing same. The recombinant hosts of the present invention provide a better morphology in tank fermentations than many known fungal host cells, such as Aspergillus, which morphology results in lower viscosity levels, and therefore improved productivity.
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申请公布号 |
US5604129(A) |
申请公布日期 |
1997.02.18 |
申请号 |
US19950457201 |
申请日期 |
1995.06.01 |
申请人 |
NOVO NORDISK BIOTECH, INC. |
发明人 |
JENSEN, EJNER B.;BOOMINATHAN, KARUPPAN C. |
分类号 |
C12N15/09;C12N1/14;C12N1/15;C12N9/02;C12N9/10;C12N9/14;C12N9/24;C12N9/88;C12N9/90;C12N15/55;C12N15/80;C12R1/645;C12R1/69;C12R1/75;(IPC1-7):C12N1/15 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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