发明名称 |
Polymeric lamellar substrate particles for drug delivery |
摘要 |
PCT No. PCT/GB96/01695 Sec. 371 Date Mar. 30, 1998 Sec. 102(e) Date Mar. 30, 1998 PCT Filed Jul. 15, 1996 PCT Pub. No. WO97/02810 PCT Pub. Date Jan. 30, 1997The invention provides a composition for delivery of an active agent comprising a plurality of lamellar particles of a biodegradable polymer which is at least in part crystalline, and an active agent adsorbed to at least most of the particles. Preferably the biodegradablepolymer is at least 5% by weight crystalline. Preferred biodegradable polymers are poly(L-lactide) (L.PLA) or copolymers or blends of L.PLA. The particles are especially useful for the immobilization of antigens or allergens for vaccines. |
申请公布号 |
AU6466596(A) |
申请公布日期 |
1997.02.10 |
申请号 |
AU19960064665 |
申请日期 |
1996.07.15 |
申请人 |
THE UNIVERSITY OF NOTTINGHAM |
发明人 |
ALLAN GERALD ARTHUR COOMBES;STANLEY STEWART DAVIS;DIANE LISA MAJOR;JOHN MICHAEL WOOD |
分类号 |
A61K9/00;A61K9/14;A61K9/16;A61K31/70;A61K38/00;A61K38/04;A61K38/22;A61K38/27;A61K38/28;A61K39/00;A61K39/08;A61K39/145;A61K39/35;A61K47/34;A61K47/48 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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