Polymorphs of Lesopitron dihydrochloride and its hydrated forms, preparation processes and compositions containing it.

摘要

It comprises the new polymorphs I and II of Lesopitron dihydrochloride, characterized by their infrared spectra and their X-ray diffraction patterns. They are obtained by crystallization of Lesopitron dihydrochloride. It also comprises the forms I-hydrate and II-hydrate, which are obtained from the corresponding polymorphs, which have a water content from 3 to 6% and from 1.5 to 2.5%, respectively. These products are used in human medicine mainly due to their pharmacological activity over the central nervous system.