发明名称 |
FORM III CRYSTALLINE (R-(R*,R*)-2-(4-FLUOROPHENYL)-BETA-DELTA-DIHYDROXY-5-(1-METHYL-ETHYL)-3-PHENYL-4-((PHENYLAMINO)CARBONYL)-1H-PYRROLE-1-HEPTANOIC ACID HEMI CALCIUM SALT (ATORVASTATIN) |
摘要 |
A novel crystalline form of [R-(R*,R*)]-2-(4-fluorophenyl)- beta , delta -dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form III is characterized by its X-ray powder diffraction and/or solid state NMR is described, as well as methods for the preparation and pharmaceutical composition of the same, which is useful as an agent for treating hyperlipidemia and hypercholesterolemia.
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申请公布号 |
WO9703958(A1) |
申请公布日期 |
1997.02.06 |
申请号 |
WO1996US11367 |
申请日期 |
1996.07.08 |
申请人 |
WARNER-LAMBERT COMPANY;MCKENZIE, ANN, T. |
发明人 |
MCKENZIE, ANN, T. |
分类号 |
A61K31/40;A61P3/06;A61P3/14;A61P43/00;C07D;C07D207/34;(IPC1-7):C07D207/34 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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