Zweifach virusinaktiviertes humanes Blutplasma, daraus herstellbare Blutplasmaderivate und Verfahren zu deren Herstellung

摘要

The invention concerns a method of producing a virally safe therapeutic biological preparation from human plasma using a detergent and retaining at least 50 % of the biological activity, the detergent being removed at the end of the method. Non-ionic surfactants, whose molecular structure comprises a hydrophobic part consisting of a linear aliphatic chain of between 8 and 10 carbon atoms, are used as detergents. The detergent treatment can be followed by a heat treatment, optionally using conventional stabilizers.