NON- beta -OXIDIZABLE FATTY ACID ANALOGUES, THEIR USES AS THERAPEUTIC ACTIVE MEDICAMENTS, AND PREPARATION THEREOF

摘要

There are disclosed compounds of the general formula (I): alkyl-X-CH2 COOR wherein alkyl represents a saturated or unsaturated hydrocarbon of 8-26 carbon atoms, X represents a sulfur atom or a selenium atom and R is hydrogen or C1-C4 alkyl. Said compounds are used for the manufacturing of medicaments for the treatment of hyperlipidemic conditions, (arteriosclerotic disease), coronary artery disease and for reducing the concentration of lipids in blood of mammals, for inhibiting oxidative modification of LDL, and for reducing proliferation of cancer cells. Methods for preparing the compounds are also disclosed.