发明名称 |
PROCESS FOR PROTEIN REFOLDING BY MEANS OF BUFFER EXCHANGE USING A CONTINUOUS STATIONARY PHASE CAPABLE OF SEPARATING PROTEINS FROM SALT |
摘要 |
Disclosed is a quick and efficient refolding process which utilizes cellulosic rolled stationary phase to rapidly separate the reduced, denatured protein from the denaturant solution, thereby promoting high protein refold yields at higher protein concentrations, while significantly decreasing the volume needed to achieve protein refolding. |
申请公布号 |
WO9704003(A2) |
申请公布日期 |
1997.02.06 |
申请号 |
WO1996US11581 |
申请日期 |
1996.07.11 |
申请人 |
AMGEN INC.;PURDUE RESEARCH FOUNDATION |
发明人 |
SEELY, ROBERT, J.;LADISCH, MICHAEL, R. |
分类号 |
C07K1/113;C07K1/14;C07K14/475;C07K14/48;C07K14/81 |
主分类号 |
C07K1/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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