EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5.ALPHA.-ANDROST-1-ENE-17.BETA.-CARBOXAMIDE

摘要

The present invention relates to the epimers: (22R)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5.alpha.-androst-1-ene-17.beta.-carboxamide and (22S)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5.alpha.-androst-1-ene-17.beta.-carboxamide useful as inhibitors of testosterone 5.alpha.-reductase enzyme, to a process for their preparation and to pharmaceutical compositions containing them.