ALIPHATIC TRICARBOXYLIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS

摘要

This invention provides processes for producing novel aliphatic tricarboxylic acid compounds, which comprise cultivating FERM BP-5153 and then isolating aliphatic tricarboxylic acid compounds from the fermentation broth. The compounds produced by these processes include aliphatic tricarboxylic acid compounds of formula (I), or its pharmaceutically acceptable salt, wherein Y is ethyl or ethenyl; and R<1>, R<2> and R<3> are independently H or C1-5 alkyl. The present invention also relates to a pharmaceutical composition comprising the same, which is useful in the treatment of hypercholesterolemia, fungal infections or the like.