Matrix metalloproteinase inhibitors

摘要

Compounds of formula (I), wherein R2 represents a group R6-A- wherein A represents a divalent straight or branched, saturated or unsaturated hydrocarbon chain of up to 12 C atoms and R6 represents hydrogen or an optionally substituted aryl, heterocyclyl, cycloalkyl or cycloalkenyl group; and R4 and R5 each independently represents hydrogen, a C1-C4 alkyl group, or an aryl(C1-C4 alkyl) group, have matrix metalloproteinase inhibitory activity.