发明名称 Polyamine derivatives of 1-aminoindan
摘要 A compound of general formula I <IMAGE> (I) wherein n is 1 or 2; R1 and R2 are each independently hydrogen, hydroxy, substituted or unsubstituted C1-4 alkyl, substituted or unsubstituted C1-4 alkoxy or halogeno; R5 is hydrogen, substituted or unsubstituted C1-4 alkyl, amino or NR6R7; R3, R4, R6 and R7 are each independently hydrogen or (CH2)m-[NH(CH2)x]y-NHR11 wherein m is from 0-5, y is from 0-5 and each x is independently from 1-5 and R11 is hydrogen or C(NH)NH2; provided that when R3 and R4 are both hydrogen, R5 is amino or NR6R7; pharmaceutically acceptable salts and optically active isomers thereof.
申请公布号 AU6452596(A) 申请公布日期 1997.02.05
申请号 AU19960064525 申请日期 1996.07.05
申请人 TEVA PHARMACEUTICAL INDUSTRIES, LTD. 发明人 GAD GILAD;VARDA GILAD;JEFFREY STERLING;YAACOV HERZIG;DAVID LERNER;ALEX VEINBERG;ISAAC MILMAN;NINA FINKELSTEIN
分类号 A61K31/135;A61K31/155;C07C211/42;C07C233/41;C07C279/12 主分类号 A61K31/135
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