Optical fiber waist refractometer

摘要

The present invention relates to a refractive index detector for a dynamic liquid sample having a fiber optic filament of a predetermined diameter with an unclad sensor region, wherein the sensor region comprises a longitudinally tapered zone wherein the diameter continuously decreases from the predetermined diameter to a minimum diameter. The invention finds use as a detector for high performance liquid chromatography and capillary zone electrophoresis.