发明名称 |
Hydrazino and hydroxyamino-14- beta -hydroxyandrostane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same |
摘要 |
The invention describes hydrazino and hydroxyamino-14 beta -hydroxyandrostane derivatives having general formula (I): <IMAGE> wherein the symbol +Z means alpha or beta configuration and A, B, R1, R2, R3, and R4 have the meanings given in the description and their use in the treatment of cardiovascular disorders such as heart failure and hypertension.
|
申请公布号 |
US5599806(A) |
申请公布日期 |
1997.02.04 |
申请号 |
US19950444366 |
申请日期 |
1995.05.18 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
CERRI, ALBERTO;BIANCHI, GIUSEPPE;FERRARI, PATRIZIA;FOLPINI, ELENA;MELLONI, PIERO |
分类号 |
A61K31/565;A61K31/575;A61K31/58;A61P9/00;A61P9/12;C07J15/00;C07J41/00;C07J43/00;(IPC1-7):A61K31/58 |
主分类号 |
A61K31/565 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|