| 摘要 |
PCT No. PCT/GB91/01934 Sec. 371 Date Apr. 30, 1993 Sec. 102(e) Date Apr. 30, 1993 PCT Filed Nov. 5, 1991 PCT Pub. No. WO92/07858 PCT Pub. Date May 14, 1992A process for the preparation of compounds of formula (I) in which Z is hydrogen or -NHZ is an activated amine group capable of reacting with a surface, the groups R are the same or different and each is a straight or branched C1-C4 alkyl group, preferably methyl, n is from 2 to 6, and X is a straight or branched C1-20 alkylene group, or X is a group of formula -(CH2CH2O)b-, or -(CH2)c-Ar-(CH2)d- where b is from 1 to 20, c and d are the same or different and each is from 0 to 5, and Ar is a para- or meta- disubstituted phenyl group (preferably a para-disubstituted phenyl group) which is optionally further substituted by one or more C1-C4 alkyl groups, or an acid addition salt thereof or a hydrate thereof, new compounds of formula (I) and salts and hydrates thereof and the use of compounds of formula (I) and salts and hydrates thereof in treating surfaces to render them more biocompatible.
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