发明名称 |
Printing molecular library arrays using deprotection agents solely in the vapor phase |
摘要 |
A method and apparatus for selectively applying a print material onto a substrate for the synthesis of an array of oligonucleotides at selected regions of a substrate. The print material includes a barrier material, a monomer sequence, a nucleoside, a deprotection agent, a carrier material, among other materials. The method and apparatus also relies upon standard DMT based chemistry, and a vapor phase deprotection agent such as solid TCA and the like.
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申请公布号 |
US5599695(A) |
申请公布日期 |
1997.02.04 |
申请号 |
US19950395604 |
申请日期 |
1995.02.27 |
申请人 |
AFFYMETRIX, INC. |
发明人 |
PEASE, R. FABIAN;MCGALL, GLENN;GOLDBERG, MARTIN J.;RAVA, RICHARD P.;FODOR, STEPHEN P. A.;GOSS, VIRGINIA;STRYER, LUBERT;WINKLER, JAMES L. |
分类号 |
B01J19/00;B41M3/00;C07H21/00;C40B40/06;C40B50/14;C40B60/14;G03F7/00;(IPC1-7):C12P19/34;G01N33/543;C07H21/02;C07K5/00 |
主分类号 |
B01J19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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