| 摘要 |
Substituted 4-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazoles and 4-(2,3-dihydro-1H-inden-1-yl)-1H-imidazoles, their optical isomers and their racemic mixtures, their salts, methods for preparing them and therapeutic compositions containing them are described. These compounds correspond to the general formula: (see formula), in which n=1 or 2, R, R2, R3 and R4, which may be the same or different, each represents a hydrogen or halogen atom, a hydroxyl group, or an alkyl or alkoxy group having 1 to 4 carbon atoms and R5 represents a hydrogen atom or an alkyl group having 1 to 4carbom atoms, with the proviso that R1, R2, R3, R4 and R5 cannot simultaneously be hydrogen when n is equal to 2. These new compounds exhibit anti-ischaemic and anti-hypertensive activities.
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