发明名称 |
Doxorubicine liposomale pegylatée ou un sel pharmaceutiquement acceptable de celle-ci |
摘要 |
The present invention relates to an improved transmembrane loading procedure for efficient loading of amphiphatic drugs into liposomes using the transmembrane gradient of ammonium and of pH. The resulting liposomes loaded with the drug are stable and safe. The procedure is equally applicable for sustained release of liposome-encapsulated drugs. The liposomes may be used in ultrasound imaging to release CO2. |
申请公布号 |
LU88856(I2) |
申请公布日期 |
1997.01.31 |
申请号 |
LU19890088856C |
申请日期 |
1989.09.27 |
申请人 |
YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM |
发明人 |
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分类号 |
A61K9/127;A61K49/22;B01J13/02 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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