Use of melatonin for the manufacture of a medicament for the treatment of benign prostatic hyperplasia

摘要

A pharmaceutical formulation for use in treating benign prostatic hyperplasia (BPH) in male humans comprises, in combination a carrier, diluent or adjuvant, (1) an effective BPH treating amount of melatonin; and optionally (2) antiandrogens, antiestrogens, growth hormones and/or inhibitors of prostatal testosterone reductase; and/or (3) oxazepam or other melatonin receptor profile modifier. The invention also relates to use of melatonin in the manufacture of a medicament, and melatonin for use as a medicament, for the treatment of BPH in male humans.