| 摘要 |
<p>Described herein are oligopeptides useful to inhibit HIV replication in virally infected individuals. In a preferred embodiment of the invention, the oligopeptide is a D-arginine nonamer having N- and C-terminal protecting groups, which, at a 5 mu m concentration, exhibits greater than 95 % inhibition of HIV replication, in a standard assay.</p> |
| 申请人 |
ALLELIX BIOPHARMACEUTICALS INC., MISSISSAUGA, ONTARIO, CA |
发明人 |
SUMNER-SMITH, MARTIN, BOLTON, ONTARIO L0P 1A0, CA;BARNETT, RICHARD W., MISSISSAUGA, ONTARIO L5B 1K2, CA;REID, LORNE, S., TORONTO, ONTARIO M6G 2T1, CA;SONENBERG, NAHUM, COTE ST. LUC, QUEBEC H4W 2S9, CA |
